SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03947

Signal sequence   MCGPSYCTLLLIAASCYILVCSHA

Length  24

Organism  Drosophila melanogaster (Fruit fly)

UniProt ID  Q9VG55,

Motif  1..24



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03947.cif

Structure  SPKB03947.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2533.08984

Aliphatic index  122.0833333

Isoelectric point  7.119437703

Charge (pH=7)   -0.160706302

Topological polar surface area  873.89

Aromaticity  0.083333333

Average rotatable bonds  3.166666667

Number of hydrogen bond donors  35

Number of hydrogen bond acceptors  37

X logP energy  -6.629

Hydropathy 



Literature Information


Title  The Drosophila hugin gene codes for myostimulatory and ecdysis-modifying neuropeptides.

DOI  10.1016/s0925-4773(02)00175-2,

Publication Year  2002

PubMed ID  12204246,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.