SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03946

Signal sequence   MMIASSLAVLYGIAIVSSMGVQSARA

Length  26

Organism  Drosophila melanogaster (Fruit fly)

UniProt ID  Q9VB68,

Motif  1..26



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  2XXL,

Predicted Structure ID  SPKB03946.cif

Structure  SPKB03946.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2627.17084

Aliphatic index  127.6923077

Isoelectric point  9.348807885

Charge (pH=7)   0.997130574

Topological polar surface area  1017.19

Aromaticity  0.038461538

Average rotatable bonds  3.346153846

Number of hydrogen bond donors  37

Number of hydrogen bond acceptors  38

X logP energy  -10.22303

Hydropathy 



Literature Information


Title  Structure-function analysis of grass clip serine protease involved in Drosophila Toll pathway activation.

DOI  10.1074/jbc.M110.182741,

Publication Year  2011

PubMed ID  21310954,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.