General Information
SPKB ID SPKB03941
Signal sequence MRKHLSWWWLATVCMLLFSHLSAVQ
Length 25
Organism Homo sapiens (Human)
UniProt ID Q9UKY0,
Motif 1..25
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB03941.cif
Physicochemical Information
Molecular weight 3044.68944
Aliphatic index 109.2
Isoelectric point 9.835414535
Charge (pH=7) 2.11752942
Topological polar surface area 1078.38
Aromaticity 0.16
Average rotatable bonds 3.8
Number of hydrogen bond donors 41
Number of hydrogen bond acceptors 38
X logP energy -3.58643
Hydropathy
Literature Information
Title The human "prion-like" protein Doppel is expressed in both Sertoli cells and spermatozoa.
Publication Year 2002
PubMed ID 12200435,
Patent ID NA,