General Information
SPKB ID SPKB03939
Signal sequence MATSTGRWLLLRLALFGFLWEASGG
Length 25
Organism Homo sapiens (Human)
UniProt ID Q9UK23,
Motif 1..25
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB03939.cif
Physicochemical Information
Molecular weight 2754.24494
Aliphatic index 105.6
Isoelectric point 10.39777148
Charge (pH=7) 0.9997528
Topological polar surface area 1035.32
Aromaticity 0.16
Average rotatable bonds 3.48
Number of hydrogen bond donors 39
Number of hydrogen bond acceptors 34
X logP energy -6.28056
Hydropathy 
Literature Information
Title Human mannose 6-phosphate-uncovering enzyme is synthesized as a proenzyme that is activated by the endoprotease furin.
Publication Year 2002
PubMed ID 12058031,
Patent ID NA,
