SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03934

Signal sequence   MPSPGTVCSLLLLGMLWLDLAMA

Length  23

Organism  Homo sapiens (Human)

UniProt ID  Q9UBU3,

Motif  1..23



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03934.cif

Structure  SPKB03934.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2433.03834

Aliphatic index  140

Isoelectric point  3.749971454

Charge (pH=7)   -1.063543932

Topological polar surface area  799.72

Aromaticity  0.043478261

Average rotatable bonds  3.260869565

Number of hydrogen bond donors  28

Number of hydrogen bond acceptors  32

X logP energy  -2.8892

Hydropathy 



Literature Information


Title  Identification and characterization of a novel gastric peptide hormone: the motilin-related peptide.

DOI  10.1053/gast.2000.9371,

Publication Year  2000

PubMed ID  10930375,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.