SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03933

Signal sequence   MVAAVLLGLSWLCSPLGA

Length  18

Organism  Homo sapiens (Human)

UniProt ID  Q9UBT3,

Motif  1..18



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03933.cif

Structure  SPKB03933.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1801.23534

Aliphatic index  157.2222222

Isoelectric point  5.922539791

Charge (pH=7)   -0.063990417

Topological polar surface area  605.48

Aromaticity  0.055555556

Average rotatable bonds  3

Number of hydrogen bond donors  22

Number of hydrogen bond acceptors  23

X logP energy  -2.5974

Hydropathy 



Literature Information


Title  Functional and structural diversity of the human Dickkopf gene family.

DOI  10.1016/s0378-1119(99)00365-0,

Publication Year  1999

PubMed ID  10570958,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.