SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03930

Signal sequence   MRLLILALLGICSLTAYIVEG

Length  21

Organism  Homo sapiens (Human)

UniProt ID  Q9UBD3,

Motif  1..21



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03930.cif

Structure  SPKB03930.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2262.83754

Aliphatic index  190.4761905

Isoelectric point  6.229383416

Charge (pH=7)   -0.063069019

Topological polar surface area  805.21

Aromaticity  0.047619048

Average rotatable bonds  3.571428571

Number of hydrogen bond donors  30

Number of hydrogen bond acceptors  29

X logP energy  -2.39983

Hydropathy 



Literature Information


Title  Signal peptide prediction based on analysis of experimentally verified cleavage sites.

DOI  10.1110/ps.04682504,

Publication Year  2004

PubMed ID  15340161,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.