SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03928

Signal sequence   MKIIIFLIVCSFVLIGVKA

Length  19

Organism  Olivierus martensii (Manchurian scorpion) (Mesobuthus martensii)

UniProt ID  Q9UAC8,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03928.cif

Structure  SPKB03928.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2107.77054

Aliphatic index  194.7368421

Isoelectric point  9.676237541

Charge (pH=7)   1.935419516

Topological polar surface area  659.39

Aromaticity  0.105263158

Average rotatable bonds  3.736842105

Number of hydrogen bond donors  24

Number of hydrogen bond acceptors  25

X logP energy  1.4853

Hydropathy 



Literature Information


Title  Covalent structures of BmK AS and BmK AS-1, two novel bioactive polypeptides purified from Chinese scorpion Buthus martensi Karsch.

DOI  10.1016/s0041-0101(98)00190-1,

Publication Year  1999

PubMed ID  10080355,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.