SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03927

Signal sequence   MHNLRNILFVITLIGQKYGLTSS

Length  23

Organism  Tachypleus tridentatus (Japanese horseshoe crab)

UniProt ID  Q9U8W8,

Motif  1..23



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03927.cif

Structure  SPKB03927.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2619.12024

Aliphatic index  131.3043478

Isoelectric point  10.45503182

Charge (pH=7)   2.087744631

Topological polar surface area  1050.54

Aromaticity  0.086956522

Average rotatable bonds  3.826086957

Number of hydrogen bond donors  37

Number of hydrogen bond acceptors  36

X logP energy  -8.62993

Hydropathy 



Literature Information


Title  Horseshoe crab acetyl group-recognizing lectins involved in innate immunity are structurally related to fibrinogen.

DOI  10.1073/pnas.96.18.10086,

Publication Year  1999

PubMed ID  10468566,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.