SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03926

Signal sequence   MHTVLYSNMKNMFQLLSFLCVSLLVAG

Length  27

Organism  Tachypleus tridentatus (Japanese horseshoe crab)

UniProt ID  Q9U8W7,

Motif  1..27



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03926.cif

Structure  SPKB03926.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3060.73914

Aliphatic index  122.5925926

Isoelectric point  8.530526343

Charge (pH=7)   1.025773226

Topological polar surface area  1105.04

Aromaticity  0.111111111

Average rotatable bonds  3.740740741

Number of hydrogen bond donors  39

Number of hydrogen bond acceptors  42

X logP energy  -7.0094

Hydropathy 



Literature Information


Title  Horseshoe crab acetyl group-recognizing lectins involved in innate immunity are structurally related to fibrinogen.

DOI  10.1073/pnas.96.18.10086,

Publication Year  1999

PubMed ID  10468566,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.