SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03924

Signal sequence   MKSYISLFFILCVIFNKNVIKC

Length  22

Organism  Plasmodium falciparum (isolate 3D7)

UniProt ID  Q9TY95,

Motif  1..22



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03924.cif

Structure  SPKB03924.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2624.29914

Aliphatic index  132.7272727

Isoelectric point  9.461084307

Charge (pH=7)   2.872299352

Topological polar surface area  899.35

Aromaticity  0.181818182

Average rotatable bonds  4

Number of hydrogen bond donors  33

Number of hydrogen bond acceptors  34

X logP energy  -2.4208

Hydropathy 



Literature Information


Title  Subcellular discharge of a serine protease mediates release of invasive malaria parasites from host erythrocytes.

DOI  10.1016/j.cell.2007.10.049,

Publication Year  2007

PubMed ID  18083098,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.