SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03923

Signal sequence   MHNYYKIVLIMVAFFAVIITFSNIQVEG

Length  28

Organism  Olivierus martensii (Manchurian scorpion) (Mesobuthus martensii)

UniProt ID  Q9TVX3,

Motif  1..28



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03923.cif

Structure  SPKB03923.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3261.93084

Aliphatic index  132.1428571

Isoelectric point  7.534170081

Charge (pH=7)   0.088672651

Topological polar surface area  1151.21

Aromaticity  0.178571429

Average rotatable bonds  3.75

Number of hydrogen bond donors  39

Number of hydrogen bond acceptors  41

X logP energy  -3.4604

Hydropathy 



Literature Information


Title  Characterization of four toxins from Buthus martensi scorpion venom, which act on apamin-sensitive Ca2+-activated K+ channels.

DOI  10.1111/j.1432-1033.1997.00457.x,

Publication Year  1997

PubMed ID  9151979,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.