SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03910

Signal sequence   MVSSATICSLLLLSMLWMDMAMA

Length  23

Organism  Rattus norvegicus (Rat)

UniProt ID  Q9QYH7,

Motif  1..23



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03910.cif

Structure  SPKB03910.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2519.16214

Aliphatic index  127.3913043

Isoelectric point  3.749971454

Charge (pH=7)   -1.063543932

Topological polar surface area  857.76

Aromaticity  0.043478261

Average rotatable bonds  3.608695652

Number of hydrogen bond donors  32

Number of hydrogen bond acceptors  36

X logP energy  -4.6998

Hydropathy 



Literature Information


Title  Ghrelin is a growth-hormone-releasing acylated peptide from stomach.

DOI  10.1038/45230,

Publication Year  1999

PubMed ID  10604470,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.