SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03905

Signal sequence   MFSGFNVFRVGISFVIMCIFYMPTVNS

Length  27

Organism  Homo sapiens (Human)

UniProt ID  Q9P2K2,

Motif  1..27



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03905.cif

Structure  SPKB03905.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3107.75474

Aliphatic index  86.2962963

Isoelectric point  8.527213491

Charge (pH=7)   0.935155858

Topological polar surface area  1060.36

Aromaticity  0.222222222

Average rotatable bonds  3.555555556

Number of hydrogen bond donors  38

Number of hydrogen bond acceptors  40

X logP energy  -5.74293

Hydropathy 



Literature Information


Title  Secretion and immunogenicity of the meningioma-associated antigen TXNDC16.

DOI  10.4049/jimmunol.1303098,

Publication Year  2014

PubMed ID  25122923,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.