SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03904

Signal sequence   MLVLGLLVAGAADG

Length  14

Organism  Homo sapiens (Human)

UniProt ID  Q9P246,

Motif  1..14



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03904.cif

Structure  SPKB03904.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1299.59134

Aliphatic index  174.2857143

Isoelectric point  3.749987361

Charge (pH=7)   -1.001569216

Topological polar surface area  478.92

Aromaticity  0

Average rotatable bonds  3

Number of hydrogen bond donors  16

Number of hydrogen bond acceptors  17

X logP energy  -2.6212

Hydropathy 



Literature Information


Title  Identification and characterization of the STIM (stromal interaction molecule) gene family: coding for a novel class of transmembrane proteins.

DOI  10.1042/0264-6021:3570673,

Publication Year  2001

PubMed ID  11463338,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.