SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03900

Signal sequence   MYLVAGDRGLAGCGHLLVSLLGLLLLLARSGTRA

Length  34

Organism  Homo sapiens (Human)

UniProt ID  Q9NZV1,

Motif  1..34



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03900.cif

Structure  SPKB03900.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3481.22154

Aliphatic index  155

Isoelectric point  9.499963167

Charge (pH=7)   2.02650481

Topological polar surface area  1356.22

Aromaticity  0.029411765

Average rotatable bonds  3.411764706

Number of hydrogen bond donors  51

Number of hydrogen bond acceptors  46

X logP energy  -10.68929

Hydropathy 



Literature Information


Title  CRIM1 regulates the rate of processing and delivery of bone morphogenetic proteins to the cell surface.

DOI  10.1074/jbc.M301247200,

Publication Year  2003

PubMed ID  12805376,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.