SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03899

Signal sequence   MGRLLRAARLPPLLSPLLLLLVGGAFLGACVA

Length  32

Organism  Homo sapiens (Human)

UniProt ID  Q9NZ53,

Motif  1..32



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03899.cif

Structure  SPKB03899.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3273.13424

Aliphatic index  167.8125

Isoelectric point  12.19926402

Charge (pH=7)   2.93599965

Topological polar surface area  1144.98

Aromaticity  0.03125

Average rotatable bonds  3.21875

Number of hydrogen bond donors  41

Number of hydrogen bond acceptors  39

X logP energy  -4.90239

Hydropathy 



Literature Information


Title  Identification of endoglycan, a member of the CD34/podocalyxin family of sialomucins.

DOI  10.1074/jbc.275.12.9001,

Publication Year  2000

PubMed ID  10722749,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.