SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03894

Signal sequence   MSLVLLSLAALCRSAVP

Length  17

Organism  Homo sapiens (Human)

UniProt ID  Q9NRM6,

Motif  1..17



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03894.cif

Structure  SPKB03894.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1744.18404

Aliphatic index  166.4705882

Isoelectric point  8.549912035

Charge (pH=7)   0.936006272

Topological polar surface area  642.72

Aromaticity  0

Average rotatable bonds  3.235294118

Number of hydrogen bond donors  24

Number of hydrogen bond acceptors  24

X logP energy  -4.81343

Hydropathy 



Literature Information


Title  A novel cytokine receptor-ligand pair. Identification, molecular characterization, and in vivo immunomodulatory activity.

DOI  10.1074/jbc.M910228199,

Publication Year  2000

PubMed ID  10749887,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.