SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03888

Signal sequence   MAMTWIVFSLWPLTVFMGHIGG

Length  22

Organism  Homo sapiens (Human)

UniProt ID  Q9NPG1,

Motif  1..22



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  8QW4,

Predicted Structure ID  SPKB03888.cif

Structure  SPKB03888.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2495.05614

Aliphatic index  101.8181818

Isoelectric point  7.550323994

Charge (pH=7)   0.08889339

Topological polar surface area  786.58

Aromaticity  0.181818182

Average rotatable bonds  3.363636364

Number of hydrogen bond donors  28

Number of hydrogen bond acceptors  30

X logP energy  -0.5918

Hydropathy 



Literature Information


Title  Signal peptide prediction based on analysis of experimentally verified cleavage sites.

DOI  10.1110/ps.04682504,

Publication Year  2004

PubMed ID  15340161,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.