General Information
SPKB ID SPKB03886
Signal sequence MAAALWGFFPVLLLLLLSGDVQS
Length 23
Organism Homo sapiens (Human)
UniProt ID Q9NPA0,
Motif 1..23
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID 6WW7,
Predicted Structure ID SPKB03886.cif
Physicochemical Information
Molecular weight 2461.98784
Aliphatic index 156.9565217
Isoelectric point 3.749987361
Charge (pH=7) -1.001569216
Topological polar surface area 831.37
Aromaticity 0.130434783
Average rotatable bonds 3.304347826
Number of hydrogen bond donors 28
Number of hydrogen bond acceptors 29
X logP energy -1.7854
Hydropathy
Literature Information
Title Structural basis for membrane insertion by the human ER membrane protein complex.
Publication Year 2020
PubMed ID 32439656,
Patent ID NA,