SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03884

Signal sequence   MLKSVFVLFLVNYLNSVRC

Length  19

Organism  Manduca sexta (Tobacco hawkmoth) (Tobacco hornworm)

UniProt ID  Q9NJ98,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03884.cif

Structure  SPKB03884.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2245.76944

Aliphatic index  143.1578947

Isoelectric point  9.447869836

Charge (pH=7)   1.934860824

Topological polar surface area  821.91

Aromaticity  0.157894737

Average rotatable bonds  3.842105263

Number of hydrogen bond donors  30

Number of hydrogen bond acceptors  29

X logP energy  -3.82263

Hydropathy 



Literature Information


Title  A beta1,3-glucan recognition protein from an insect, Manduca sexta, agglutinates microorganisms and activates the phenoloxidase cascade.

DOI  10.1074/jbc.275.11.7505,

Publication Year  2000

PubMed ID  10713054,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.