SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03883

Signal sequence   MKVFFAVLITLFICSMIIGIHG

Length  22

Organism  Olivierus martensii (Manchurian scorpion) (Mesobuthus martensii)

UniProt ID  Q9NII7,

Motif  1..22



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03883.cif

Structure  SPKB03883.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2454.13114

Aliphatic index  155

Isoelectric point  8.552755748

Charge (pH=7)   1.026623641

Topological polar surface area  769.58

Aromaticity  0.136363636

Average rotatable bonds  3.636363636

Number of hydrogen bond donors  28

Number of hydrogen bond acceptors  30

X logP energy  0.1285

Hydropathy 



Literature Information


Title  Purification, characterization, and synthesis of three novel toxins from the Chinese scorpion Buthus martensi, which act on K+ channels.

DOI  10.1021/bi971044w,

Publication Year  1997

PubMed ID  9354615,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.