SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03882

Signal sequence   MKIFSILLVALIICSISICTEA

Length  22

Organism  Olivierus martensii (Manchurian scorpion) (Mesobuthus martensii)

UniProt ID  Q9NBG9,

Motif  1..22



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03882.cif

Structure  SPKB03882.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2382.01614

Aliphatic index  181.8181818

Isoelectric point  6.13535235

Charge (pH=7)   -0.124485044

Topological polar surface area  818.66

Aromaticity  0.045454545

Average rotatable bonds  3.636363636

Number of hydrogen bond donors  31

Number of hydrogen bond acceptors  32

X logP energy  -3.1033

Hydropathy 



Literature Information


Title  Martentoxin, a novel K+-channel-blocking peptide: purification, cDNA and genomic cloning, and electrophysiological and pharmacological characterization.

DOI  10.1046/j.1471-4159.2003.01516.x,

Publication Year  2003

PubMed ID  12558995,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.