SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03870

Signal sequence   MKKSAAVVAGAIMALGMAAPAFA

Length  23

Organism  Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)

UniProt ID  Q9L1J9,

Motif  1..23



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Cell wall

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03870.cif

Structure  SPKB03870.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2177.70974

Aliphatic index  98.26086957

Isoelectric point  10.80537956

Charge (pH=7)   1.997394232

Topological polar surface area  767

Aromaticity  0.043478261

Average rotatable bonds  3.043478261

Number of hydrogen bond donors  26

Number of hydrogen bond acceptors  30

X logP energy  -5.8315

Hydropathy 



Literature Information


Title  A novel class of secreted hydrophobic proteins is involved in aerial hyphae formation in Streptomyces coelicolor by forming amyloid-like fibrils.

DOI  10.1101/gad.264303,

Publication Year  2003

PubMed ID  12832396,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.