SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03867

Signal sequence   MCSRGDANAAGAAAARRVTGLCYNMGLLIALALLCLFSLAEA

Length  42

Organism  Rattus norvegicus (Rat)

UniProt ID  Q9JLA3,

Motif  1..42



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03867.cif

Structure  SPKB03867.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  4244.04674

Aliphatic index  116.6666667

Isoelectric point  8.041815276

Charge (pH=7)   0.81342141

Topological polar surface area  1683.82

Aromaticity  0.047619048

Average rotatable bonds  3.30952381

Number of hydrogen bond donors  63

Number of hydrogen bond acceptors  59

X logP energy  -17.17739

Hydropathy 



Literature Information


Title  Cloning and characterization of mammalian UDP-glucose glycoprotein: glucosyltransferase and the development of a specific substrate for this enzyme.

DOI  10.1093/glycob/10.4.403,

Publication Year  2000

PubMed ID  10764828,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.