SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03865

Signal sequence   MARSPQGLLMLLLLHYLIVALDYHKANG

Length  28

Organism  Mus musculus (Mouse)

UniProt ID  Q9JI59,

Motif  1..28



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03865.cif

Structure  SPKB03865.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3151.82164

Aliphatic index  146.4285714

Isoelectric point  9.150271992

Charge (pH=7)   1.178249792

Topological polar surface area  1169.68

Aromaticity  0.071428571

Average rotatable bonds  3.678571429

Number of hydrogen bond donors  40

Number of hydrogen bond acceptors  41

X logP energy  -5.27793

Hydropathy 



Literature Information


Title  Vascular endothelial junction-associated molecule, a novel member of the immunoglobulin superfamily, is localized to intercellular boundaries of endothelial cells.

DOI  10.1074/jbc.M003189200,

Publication Year  2000

PubMed ID  10779521,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.