General Information
SPKB ID SPKB03856
Signal sequence MGSLSNYALLQLTLTAFLTILVQPQH
Length 26
Organism Homo sapiens (Human)
UniProt ID Q9H9K5,
Motif 1..26
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB03856.cif
Physicochemical Information
Molecular weight 2873.40314
Aliphatic index 138.8461538
Isoelectric point 7.542349207
Charge (pH=7) 0.088042976
Topological polar surface area 1104.45
Aromaticity 0.076923077
Average rotatable bonds 3.538461538
Number of hydrogen bond donors 37
Number of hydrogen bond acceptors 39
X logP energy -8.5707
Hydropathy
Literature Information
Title HEMO, an ancestral endogenous retroviral envelope protein shed in the blood of pregnant women and expressed in pluripotent stem cells and tumors.
Publication Year 2017
PubMed ID 28739914,
Patent ID NA,