General Information
SPKB ID SPKB03854
Signal sequence MDLLQFLAFLFVLLLSGMGATG
Length 22
Organism Homo sapiens (Human)
UniProt ID Q9H6E4,
Motif 1..22
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB03854.cif
Physicochemical Information
Molecular weight 2357.89454
Aliphatic index 146.3636364
Isoelectric point 3.749987361
Charge (pH=7) -1.001569216
Topological polar surface area 795.27
Aromaticity 0.136363636
Average rotatable bonds 3.5
Number of hydrogen bond donors 27
Number of hydrogen bond acceptors 29
X logP energy -2.1606
Hydropathy 
Literature Information
Title CCDC134, a novel secretory protein, inhibits activation of ERK and JNK, but not p38 MAPK.
DOI 10.1007/s00018-007-7448-5,
Publication Year 2008
PubMed ID 18087676,
Patent ID NA,
