General Information
SPKB ID SPKB03853
Signal sequence MAGLNCGVSIALLGVLLLGAARLPRGAEA
Length 29
Organism Homo sapiens (Human)
UniProt ID Q9H5V8,
Motif 1..29
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB03853.cif
Physicochemical Information
Molecular weight 2807.40854
Aliphatic index 148.2758621
Isoelectric point 8.549845238
Charge (pH=7) 0.937778084
Topological polar surface area 1093.75
Aromaticity 0
Average rotatable bonds 3.172413793
Number of hydrogen bond donors 39
Number of hydrogen bond acceptors 37
X logP energy -9.62196
Hydropathy 
Literature Information
Title Subtractive immunization using highly metastatic human tumor cells identifies SIMA135/CDCP1, a 135 kDa cell surface phosphorylated glycoprotein antigen.
Publication Year 2003
PubMed ID 12660814,
Patent ID NA,
