SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03849

Signal sequence   MAPARAGFCPLLLLLLLGLWVAEIPVSA

Length  28

Organism  Homo sapiens (Human)

UniProt ID  Q9H1E1,

Motif  1..28



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03849.cif

Structure  SPKB03849.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2935.66534

Aliphatic index  163.9285714

Isoelectric point  6.232433001

Charge (pH=7)   -0.062218605

Topological polar surface area  957.87

Aromaticity  0.071428571

Average rotatable bonds  3.142857143

Number of hydrogen bond donors  33

Number of hydrogen bond acceptors  34

X logP energy  -1.13433

Hydropathy 



Literature Information


Title  RNase 7, a novel innate immune defense antimicrobial protein of healthy human skin.

DOI  10.1074/jbc.M207587200,

Publication Year  2002

PubMed ID  12244054,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.