SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03837

Signal sequence   MNKIYALKYCHATGGLIAVSELASRVMKKAARGSLLALFNLSLYGAFLSASQA

Length  53

Organism  Escherichia coli O127:H6 (strain E2348/69 / EPEC)

UniProt ID  Q9EZE7,

Motif  1..53



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Periplasmic space

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03837.cif

Structure  SPKB03837.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  5620.67524

Aliphatic index  110.754717

Isoelectric point  10.36428333

Charge (pH=7)   5.024955796

Topological polar surface area  2201.95

Aromaticity  0.094339623

Average rotatable bonds  3.566037736

Number of hydrogen bond donors  80

Number of hydrogen bond acceptors  78

X logP energy  -19.85806

Hydropathy 



Literature Information


Title  Protein secretion by enteropathogenic Escherichia coli is essential for transducing signals to epithelial cells.

DOI  10.1073/pnas.92.17.7991,

Publication Year  1995

PubMed ID  7644526,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.