SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03836

Signal sequence   MLCFWRTSHVAVLLIWGVFAAES

Length  23

Organism  Rattus norvegicus (Rat)

UniProt ID  Q9ES58,

Motif  1..23



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03836.cif

Structure  SPKB03836.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2637.15554

Aliphatic index  118.6956522

Isoelectric point  7.360093818

Charge (pH=7)   0.028690486

Topological polar surface area  923.67

Aromaticity  0.173913043

Average rotatable bonds  3.47826087

Number of hydrogen bond donors  35

Number of hydrogen bond acceptors  32

X logP energy  -3.01703

Hydropathy 



Literature Information


Title  Lymphoid/neuronal cell surface OX2 glycoprotein recognizes a novel receptor on macrophages implicated in the control of their function.

DOI  10.1016/s1074-7613(00)00023-6,

Publication Year  2000

PubMed ID  10981966,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.