SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03835

Signal sequence   MGRAGGGGPGWGPPPVLLLLGVTLVLTAGA

Length  30

Organism  Rattus norvegicus (Rat)

UniProt ID  Q9ERQ6,

Motif  1..30



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03835.cif

Structure  SPKB03835.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2785.34324

Aliphatic index  117

Isoelectric point  10.55000222

Charge (pH=7)   0.997980988

Topological polar surface area  990.21

Aromaticity  0.033333333

Average rotatable bonds  2.7

Number of hydrogen bond donors  33

Number of hydrogen bond acceptors  35

X logP energy  -8.02883

Hydropathy 



Literature Information


Title  Neuroglycan C, a novel membrane-spanning chondroitin sulfate proteoglycan that is restricted to the brain.

DOI  10.1074/jbc.270.45.26876,

Publication Year  1995

PubMed ID  7592931,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.