SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03832

Signal sequence   MGVGGTSASDTALSLCPT

Length  18

Organism  Gallus gallus (Chicken)

UniProt ID  Q9DF69,

Motif  1..18



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03832.cif

Structure  SPKB03832.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1667.86654

Aliphatic index  70.55555556

Isoelectric point  3.749971454

Charge (pH=7)   -1.063543932

Topological polar surface area  707.91

Aromaticity  0

Average rotatable bonds  2.833333333

Number of hydrogen bond donors  26

Number of hydrogen bond acceptors  28

X logP energy  -11.8948

Hydropathy 



Literature Information


Title  Chicken acidic leucine-rich EGF-like domain containing brain protein (CALEB), a neural member of the EGF family of differentiation factors, is implicated in neurite formation.

DOI  10.1083/jcb.136.4.895,

Publication Year  1997

PubMed ID  9049254,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.