SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03829

Signal sequence   MMISTAYQSLFLTALFSAISIAVG

Length  24

Organism  Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)

UniProt ID  Q9C0Y4,

Motif  1..24



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03829.cif

Structure  SPKB03829.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2536.03944

Aliphatic index  126.25

Isoelectric point  6.093198033

Charge (pH=7)   -0.002866115

Topological polar surface area  917.32

Aromaticity  0.125

Average rotatable bonds  3.375

Number of hydrogen bond donors  33

Number of hydrogen bond acceptors  35

X logP energy  -6.8715

Hydropathy 



Literature Information


Title  Carboxyl group of residue Asp647 as possible proton donor in catalytic reaction of alpha-glucosidase from Schizosaccharomyces pombe.

DOI  10.1046/j.1432-1327.2001.02104.x,

Publication Year  2001

PubMed ID  11298744,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.