SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03826

Signal sequence   MAAAAATKILLCLPLLLLLSGWSRA

Length  25

Organism  Homo sapiens (Human)

UniProt ID  Q9BZM5,

Motif  1..25



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  8IMX,

Predicted Structure ID  SPKB03826.cif

Structure  SPKB03826.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2597.25894

Aliphatic index  164.4

Isoelectric point  9.833242293

Charge (pH=7)   1.935711238

Topological polar surface area  917.33

Aromaticity  0.04

Average rotatable bonds  3.32

Number of hydrogen bond donors  34

Number of hydrogen bond acceptors  33

X logP energy  -4.13003

Hydropathy 



Literature Information


Title  A novel secreted tumor antigen with a glycosylphosphatidylinositol-anchored structure ubiquitously expressed in human cancers.

DOI  10.1006/bbrc.2001.5149,

Publication Year  2001

PubMed ID  11444831,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.