General Information
SPKB ID SPKB03826
Signal sequence MAAAAATKILLCLPLLLLLSGWSRA
Length 25
Organism Homo sapiens (Human)
UniProt ID Q9BZM5,
Motif 1..25
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID 8IMX,
Predicted Structure ID SPKB03826.cif
Physicochemical Information
Molecular weight 2597.25894
Aliphatic index 164.4
Isoelectric point 9.833242293
Charge (pH=7) 1.935711238
Topological polar surface area 917.33
Aromaticity 0.04
Average rotatable bonds 3.32
Number of hydrogen bond donors 34
Number of hydrogen bond acceptors 33
X logP energy -4.13003
Hydropathy
Literature Information
Title A novel secreted tumor antigen with a glycosylphosphatidylinositol-anchored structure ubiquitously expressed in human cancers.
Publication Year 2001
PubMed ID 11444831,
Patent ID NA,