SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03824

Signal sequence   MGVLGRVLLWLQLCALTQA

Length  19

Organism  Homo sapiens (Human)

UniProt ID  Q9BXJ7,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03824.cif

Structure  SPKB03824.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2085.59684

Aliphatic index  164.2105263

Isoelectric point  8.549912035

Charge (pH=7)   0.936006272

Topological polar surface area  771.22

Aromaticity  0.052631579

Average rotatable bonds  3.578947368

Number of hydrogen bond donors  28

Number of hydrogen bond acceptors  26

X logP energy  -3.40213

Hydropathy 



Literature Information


Title  The functional cobalamin (vitamin B12)-intrinsic factor receptor is a novel complex of cubilin and amnionless.

DOI  10.1182/blood-2003-08-2852,

Publication Year  2004

PubMed ID  14576052,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.