General Information
SPKB ID SPKB03824
Signal sequence MGVLGRVLLWLQLCALTQA
Length 19
Organism Homo sapiens (Human)
UniProt ID Q9BXJ7,
Motif 1..19
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB03824.cif
Physicochemical Information
Molecular weight 2085.59684
Aliphatic index 164.2105263
Isoelectric point 8.549912035
Charge (pH=7) 0.936006272
Topological polar surface area 771.22
Aromaticity 0.052631579
Average rotatable bonds 3.578947368
Number of hydrogen bond donors 28
Number of hydrogen bond acceptors 26
X logP energy -3.40213
Hydropathy
Literature Information
Title The functional cobalamin (vitamin B12)-intrinsic factor receptor is a novel complex of cubilin and amnionless.
DOI 10.1182/blood-2003-08-2852,
Publication Year 2004
PubMed ID 14576052,
Patent ID NA,