SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03820

Signal sequence   MAAAWPSGPSAPEAVTARLVGVLWFVSVTTGPWGAVA

Length  37

Organism  Homo sapiens (Human)

UniProt ID  Q9BX74,

Motif  1..37



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03820.cif

Structure  SPKB03820.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3711.29614

Aliphatic index  89.72972973

Isoelectric point  6.410149741

Charge (pH=7)   -0.000243889

Topological polar surface area  1343.71

Aromaticity  0.108108108

Average rotatable bonds  2.783783784

Number of hydrogen bond donors  47

Number of hydrogen bond acceptors  47

X logP energy  -10.99593

Hydropathy 



Literature Information


Title  beta -Amyloid peptide-induced apoptosis regulated by a novel protein containing a g protein activation module.

DOI  10.1074/jbc.M011161200,

Publication Year  2001

PubMed ID  11278849,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.