SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03818

Signal sequence   MGTQEGWCLLLCLALSGA

Length  18

Organism  Homo sapiens (Human)

UniProt ID  Q9BX59,

Motif  1..18



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03818.cif

Structure  SPKB03818.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1866.23844

Aliphatic index  119.4444444

Isoelectric point  3.849941048

Charge (pH=7)   -1.12419001

Topological polar surface area  694.66

Aromaticity  0.055555556

Average rotatable bonds  3.333333333

Number of hydrogen bond donors  26

Number of hydrogen bond acceptors  26

X logP energy  -5.3555

Hydropathy 



Literature Information


Title  Signal peptide prediction based on analysis of experimentally verified cleavage sites.

DOI  10.1110/ps.04682504,

Publication Year  2004

PubMed ID  15340161,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.