SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03815

Signal sequence   MIFLLLMLSLELQLHQIAA

Length  19

Organism  Homo sapiens (Human)

UniProt ID  Q9BQ51,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03815.cif

Structure  SPKB03815.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2197.76544

Aliphatic index  195.2631579

Isoelectric point  5.363507222

Charge (pH=7)   -0.909331487

Topological polar surface area  759.51

Aromaticity  0.052631579

Average rotatable bonds  3.947368421

Number of hydrogen bond donors  25

Number of hydrogen bond acceptors  27

X logP energy  -0.3178

Hydropathy 



Literature Information


Title  Signal peptide prediction based on analysis of experimentally verified cleavage sites.

DOI  10.1110/ps.04682504,

Publication Year  2004

PubMed ID  15340161,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.