SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03814

Signal sequence   MKISFVLLLTLFICSIGWSEA

Length  21

Organism  Mesobuthus eupeus (Lesser Asian scorpion) (Buthus eupeus)

UniProt ID  Q9BKB7,

Motif  1..21



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03814.cif

Structure  SPKB03814.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2371.92144

Aliphatic index  148.5714286

Isoelectric point  6.231833229

Charge (pH=7)   -0.062510328

Topological polar surface area  805.35

Aromaticity  0.142857143

Average rotatable bonds  3.666666667

Number of hydrogen bond donors  30

Number of hydrogen bond acceptors  30

X logP energy  -2.0319

Hydropathy 



Literature Information


Title  An ERG channel inhibitor from the scorpion Buthus eupeus.

DOI  10.1074/jbc.M005973200,

Publication Year  2001

PubMed ID  11136720,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.