SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03809

Signal sequence   MMTRWALVVFVVLMLDRILFVPG

Length  23

Organism  Mus musculus (Mouse)

UniProt ID  Q99ML8,

Motif  1..23



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03809.cif

Structure  SPKB03809.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2707.43554

Aliphatic index  152.173913

Isoelectric point  10.39776887

Charge (pH=7)   0.998424161

Topological polar surface area  891.85

Aromaticity  0.130434783

Average rotatable bonds  3.695652174

Number of hydrogen bond donors  32

Number of hydrogen bond acceptors  31

X logP energy  0.58264

Hydropathy 



Literature Information


Title  Posttranslational processing of human and mouse urocortin 2: characterization and bioactivity of gene products.

DOI  10.1210/en.2012-2011,

Publication Year  2013

PubMed ID  23493376,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.