General Information
SPKB ID SPKB03807
Signal sequence MRFFCARCCSFGPEMPAVQLLLLACLVWDVGA
Length 32
Organism Homo sapiens (Human)
UniProt ID Q99972,
Motif 1..32
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB03807.cif
Physicochemical Information
Molecular weight 3548.33384
Aliphatic index 100.625
Isoelectric point 6.103521343
Charge (pH=7) -0.24769958
Topological polar surface area 1225.35
Aromaticity 0.125
Average rotatable bonds 3.40625
Number of hydrogen bond donors 46
Number of hydrogen bond acceptors 45
X logP energy -6.21826
Hydropathy 
Literature Information
Title Dual localization of wild-type myocilin in the endoplasmic reticulum and extracellular compartment likely occurs due to its incomplete secretion.
DOI NA,
Publication Year 2009
PubMed ID 19287508,
Patent ID NA,
