General Information
SPKB ID SPKB03801
Signal sequence MTGERPSTALPDRRWGPRILGFWGGCRVWVFAAIFLLLSLAASWSKA
Length 47
Organism Homo sapiens (Human)
UniProt ID Q99519,
Motif 1..47
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB03801.cif
Physicochemical Information
Molecular weight 5249.19074
Aliphatic index 91.4893617
Isoelectric point 11.934564
Charge (pH=7) 3.9379196
Topological polar surface area 1970.21
Aromaticity 0.14893617
Average rotatable bonds 3.425531915
Number of hydrogen bond donors 74
Number of hydrogen bond acceptors 64
X logP energy -13.00245
Hydropathy 
Literature Information
Title Molecular mechanism of lysosomal sialidase deficiency in galactosialidosis involves its rapid degradation.
DOI 10.1042/bj3300641,
Publication Year 1998
PubMed ID 9480870,
Patent ID NA,
