General Information
SPKB ID SPKB03790
Signal sequence MGRGWGFLFGLLGAVWLLSSGHG
Length 23
Organism Homo sapiens (Human)
UniProt ID Q96HE7,
Motif 1..23
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB03790.cif
Physicochemical Information
Molecular weight 2418.84414
Aliphatic index 101.7391304
Isoelectric point 10.5517587
Charge (pH=7) 1.088890079
Topological polar surface area 866.14
Aromaticity 0.173913043
Average rotatable bonds 3.260869565
Number of hydrogen bond donors 32
Number of hydrogen bond acceptors 29
X logP energy -4.70973
Hydropathy 
Literature Information
Title The C-terminal domain of yeast Ero1p mediates membrane localization and is essential for function.
DOI 10.1016/s0014-5793(01)03034-4,
Publication Year 2001
PubMed ID 11707280,
Patent ID NA,
