General Information
SPKB ID SPKB03780
Signal sequence MAAAMPLALLVLLLLGPGGWC
Length 21
Organism Homo sapiens (Human)
UniProt ID Q969N2,
Motif 1..21
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID 7WLD,
Predicted Structure ID SPKB03780.cif
Physicochemical Information
Molecular weight 2110.70514
Aliphatic index 162.8571429
Isoelectric point 5.922539791
Charge (pH=7) -0.063990417
Topological polar surface area 643.53
Aromaticity 0.047619048
Average rotatable bonds 3
Number of hydrogen bond donors 22
Number of hydrogen bond acceptors 25
X logP energy 0.2192
Hydropathy
Literature Information
Title PIG-S and PIG-T, essential for GPI anchor attachment to proteins, form a complex with GAA1 and GPI8.
Publication Year 2001
PubMed ID 11483512,
Patent ID NA,