SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03776

Signal sequence   MAAINVIFISGAIALFALTGSC

Length  22

Organism  Halocynthia roretzi (Sea squirt) (Cynthia roretzi)

UniProt ID  Q966V2,

Motif  1..22



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03776.cif

Structure  SPKB03776.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2183.65194

Aliphatic index  142.2727273

Isoelectric point  5.922539791

Charge (pH=7)   -0.063990417

Topological polar surface area  778.2

Aromaticity  0.090909091

Average rotatable bonds  3.136363636

Number of hydrogen bond donors  28

Number of hydrogen bond acceptors  29

X logP energy  -5.7169

Hydropathy 



Literature Information


Title  Spermosin, a trypsin-like protease from ascidian sperm: cDNA cloning, protein structures and functional analysis.

DOI  10.1046/j.0014-2956.2001.02696.x,

Publication Year  2002

PubMed ID  11856325,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.