General Information
SPKB ID SPKB03774
Signal sequence MVKMQVIFIAFIAVIACSMVYG
Length 22
Organism Olivierus martensii (Manchurian scorpion) (Mesobuthus martensii)
UniProt ID Q95P90,
Motif 1..22
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB03774.cif
Physicochemical Information
Molecular weight 2435.10034
Aliphatic index 137.2727273
Isoelectric point 8.522939048
Charge (pH=7) 0.934864135
Topological polar surface area 783.99
Aromaticity 0.136363636
Average rotatable bonds 3.590909091
Number of hydrogen bond donors 28
Number of hydrogen bond acceptors 31
X logP energy -0.9118
Hydropathy
Literature Information
Title Charaterization of bumarsin, a 3-hydroxy-3-methylglutaryl-coenzyme reductase inhibitor from Mesobuthus martensii Karsch venom.
DOI 10.1016/j.toxicon.2012.04.352,
Publication Year 2012
PubMed ID 22575281,
Patent ID NA,