SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03771

Signal sequence   MGELMAFLLPLIIVLMVKHSDS

Length  22

Organism  Homo sapiens (Human)

UniProt ID  Q95460,

Motif  1..22



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03771.cif

Structure  SPKB03771.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2458.07374

Aliphatic index  155

Isoelectric point  5.454297225

Charge (pH=7)   -0.909180037

Topological polar surface area  835.39

Aromaticity  0.045454545

Average rotatable bonds  3.727272727

Number of hydrogen bond donors  28

Number of hydrogen bond acceptors  32

X logP energy  -1.7078

Hydropathy 



Literature Information


Title  Biochemical features of the MHC-related protein 1 consistent with an immunological function.

DOI  10.4049/jimmunol.170.12.6090,

Publication Year  2003

PubMed ID  12794138,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.