General Information
SPKB ID SPKB03762
Signal sequence MAVTDSLSRAATVLATVLLLSFGSVAA
Length 27
Organism Homo sapiens (Human)
UniProt ID Q92643,
Motif 1..27
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID 7W72,
Predicted Structure ID SPKB03762.cif
Physicochemical Information
Molecular weight 2665.14074
Aliphatic index 137.4074074
Isoelectric point 6.338718596
Charge (pH=7) -0.001572528
Topological polar surface area 1060.73
Aromaticity 0.037037037
Average rotatable bonds 3.148148148
Number of hydrogen bond donors 39
Number of hydrogen bond acceptors 38
X logP energy -11.54623
Hydropathy
Literature Information
Title PIG-S and PIG-T, essential for GPI anchor attachment to proteins, form a complex with GAA1 and GPI8.
Publication Year 2001
PubMed ID 11483512,
Patent ID NA,